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Updated: Sep 15, 2025

Isolation and Functional Analysis of Mitochondria from Cultured Cells and Mouse Tissue
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mtKO:用于线粒体研究的专门指南RNA库

Karambir Kaur1, Javeria Zaheer1, Fengchao Lang1

  • 1Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892.

Proceedings of the National Academy of Sciences of the United States of America
|July 17, 2025
PubMed
概括

线粒体在癌症中至关重要. 一个新的CRISPR屏幕揭示了抗氧化酶SOD2对于IDH1-突变癌症至关重要,突出了Krebs周期缺陷瘤的潜在治疗标.

关键词:
这是一个CRISPR屏幕.一个IDH1一个IDH1这就是SOD2的原因.代谢 代谢 代谢 代谢线粒体中的线粒体.

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