在局部加热的影响下,皮肤温度振荡的相位逆转
Rodion Stepanov1, Sergey Podtaev1
1Institute of Continuous Media Mechanics, Korolev str. 1, Perm, 614013, Russia.
Journal of thermal biology
|July 17, 2025
概括
局部加热揭示了皮肤血流 (SkBF) 如何影响皮肤温度振荡 (STO). STO振幅和相位的变化为微血管功能和热力学提供了洞察力.
科学领域:
- 生理学 生理学 生理学
- 生物物理学的生物物理.
- 热医学是一种热医学.
背景情况:
- 皮肤血流 (SkBF) 和皮肤温度振荡 (STO) 是微血管功能的关键指标.
- 了解局部加热期间的STO动态对于评估组织中的热调节和热传递至关重要.
研究的目的:
- 为了研究STO相位和振幅的变化,以应对局部加热.
- 探索SkBF,组织温度和STO特征之间的关系.
主要方法:
- 在局部加热过程中测量了10名健康参与者的手指 (食指,中指,戒指) 的皮肤温度振荡.
- 分析了STO振幅和相变,以及手指间的相关性.
- 基于传热方程和时间依赖的 perfusion 开发了一个数学模型来模拟 STO 动态.
主要成果:
- 起初,STO振幅在各指 (食指,中指,戒指) 之间是相似的和相关的.
- 在加热过程中,食指的STO振幅下降,然后恢复,相位逆转导致与其他手指的负相关性.
- 中指和戒指的STO相关性仍然很高;数学建模将STO振幅/阶段与平均组织温度联系起来.
结论:
- STO相位和振幅由平均组织温度调节,受微血管血管扩张和热边界条件的影响.
- 该研究提出了一种结合STO相位和振幅分析的新方法.
- 这项研究有可能通过分析微血管功能和热力学来改善血管健康评估的诊断工具.
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