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Updated: Jun 27, 2026

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在唐氏综合征模型中,大脑代谢和行为变化

Larissa Estessi de Souza1, Chiara Maria Righini2, Dimitri Brigide de Almeida Mantovani2

  • 1Laboratory of Nuclear Medicine (LIM 43), Department of Radiology and Oncology, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil; Department of Nuclear Medicine, Hospital Israelita Albert Einstein, São Paulo, Brazil.

Nuclear medicine and biology
|July 17, 2025
PubMed
概括

这项研究监测了唐氏综合征 Ts65Dn 鼠标模型的整个寿命. 三体小鼠显示早期大脑网络中断,与神经炎症和与衰老相关的功能障碍有关.

关键词:
大脑的连接性 大脑的连接性唐氏综合征是什么意思 唐氏综合征葡萄糖的新陈代谢.神经炎症是一种神经炎症.的 Ts65Dnn 的情况.[(18) F]FDG PET PET 是一个很好的方法.

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