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耐力经验丰富的运动员 (VENTOUX) 中心室节律失常和心脏纤维化
Wasim Javed1, Ioannis Botis1, Ze Min Goh1
1Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds/Leeds Teaching Hospitals National Health Service Trust, United Kingdom (W.J., I.B., Z.M.G., M.S., B.B., R.T., M.F., L.G., J.G., J.P.G., S.P., P.P.S.).
Circulation. Cardiovascular imaging
|July 17, 2025
概括
老年男性耐力运动员心肌纤维化与心室心律失常的风险更高有关. 这一发现强调了心脏查在这个人群中的重要性,以防止心脏突然死亡.
科学领域:
- 心脏病学 心脏病学
- 运动医学 运动医学
- 心脏成像 - - 心脏成像
背景情况:
- 运动员突然心脏病死亡通常是由于初级心律失常,特别是在年长的男性中.
- 心肌纤维化与非血性心肌病症中的心律失常有关,但其在无症状耐力运动员中的作用尚不清楚.
- 这项研究调查了经验丰富的男性耐力运动员心肌纤维化和心室节律失常之间的联系.
研究的目的:
- 为了确定心肌纤维化,通过心血管磁共振检测,与无症状的资深男性耐力运动员的事件心室节律失常有关.
- 在长期随访中评估心肌纤维化对心室节律失常的预测价值.
主要方法:
- 一项前性观察性队列研究,对106名无症状的男性竞技骑自行车/三项运动员 (年龄≥50岁) 进行了广泛的运动史.
- 参与者接受了心血管磁共振 (CMR) 与晚期加多增强 (LGE),压力 perfusion 成像和运动测试.
- 植入式循环记录器用于长期监测心室心律失常.
主要成果:
- 焦点心肌纤维化存在于47.2%的运动员中,主要存在于基底下侧左心室.
- 在随访期间,21.7%的运动员出现了心室节律失常,包括持续和不持续的心室低心率.
- 心肌纤维化 (HR 4.7) 和左心室末端透缩体积增加 (HR 1.4) 与心室失常风险增加有关.
- 在调整左心室扩张后,心肌纤维化仍然是一个独立的预测因素.
结论:
- 心肌纤维化独立地与男性经验丰富的耐力运动员心室节律失常的发展有关.
- 在右心室插入点的晚期加多增强与心室心律失常无关.
- 需要进一步的研究来澄清心肌纤维化是否直接引起心律失常或是潜在疾病的标志物.
关键词:
运动员运动员运动员扩张 扩张 扩张纤维化 纤维化perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion 这种方法通常被认为是最常见的方法之一,因为它可以让一个人的身体变得更加舒适,可以让一个人的身体变得更加舒适.相关概念视频
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