大麻使用与儿科患者下尿道症状有关-一项大型索赔数据库研究
Aurora J Grutman1, Mohammad Elmojtaba Gumma2, Nicole Page2
1The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD; Johns Hopkins University School of Medicine, Baltimore, MD.
Urology
|July 17, 2025
概括
大麻使用障碍 (CUD) 与儿科患者下泌尿道症状 (LUTS) 的诊断增加有关. 这包括像盆腔疼痛,膀过活,尿障和尿路感染在男性和女性等条件.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 儿科医学 儿科医学
- 成 药物 药物 药物 药物
背景情况:
- 下尿道症状 (LUTS) 在儿科患者中很常见.
- 大麻使用障碍 (CUD) 是青少年日益关注的问题.
- 儿科中CUD和LUTS之间的关联仍未得到充分研究.
研究的目的:
- 确定大麻使用障碍 (CUD) 的诊断是否与18岁以下患者的下泌尿道症状 (LUTS) 有关.
- 为了比较患有CUD和没有CUD的儿科患者中LUTS诊断的发生率.
主要方法:
- 使用TriNetX研究网络进行的回顾性队列研究.
- 包括18岁以下的男性和女性患者,有或没有CUD.
- 对人口因素和并发症的倾向性得分进行匹配,然后对新的LUTS诊断进行5年结果评估.
主要成果:
- 与对照组相比,在患有CUD的女性儿科患者中,观察到盆腔疼痛,膀过活,尿障和尿路感染 (UTI) 的新诊断显著增加.
- 与对照组相比,患有CUD的男性儿科患者显示,盆腔疼痛,尿障和尿路感染的新诊断显著增加.
- 该研究确定了CUD和LUTS诊断增加在儿科两性之间存在明显的关联.
结论:
- 被诊断为CUD的儿科患者表现出明显更高的新发性LUTS发病率.
- 需要进一步的研究,以了解大麻素如何影响青少年尿路和盆底功能的具体机制.
- 这些发现突出了一个潜在的公共卫生问题,即将青少年CUD与泌尿系统疾病联系起来.
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