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精准医学在中国瘤学环境中的成本效益:系统审查和元分析协议

Qian Jiang¹, Dongni Zheng^2,3, Huan Li³

¹Department of Pharmacy, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.

|July 17, 2025

概括

本系统性审查评估了中国基因组向性癌症药物的成本效益. 结果将为低收入和中等收入国家准确医学 (PM) 的可访问性提供信息.

科学领域:

在瘤学瘤学.
卫生经济学卫生经济学
精准医学是一门精准的医学.

背景情况:

基因组向性瘤药物代表了精准医学 (PM) 的重大进步.
在人口密的中低收入国家中国,这些药物的成本效益在很大程度上是未知的.
现有的中文系统审查没有解决这个问题.

研究的目的:

对中国基因组向抗癌药物的成本效益进行系统审查和元分析.
综合现有证据,阐述精密瘤学在中国医疗保健环境中的经济价值.
确定影响这些向治疗的成本效益的因素.

主要方法:

在英语和中文数据库 (MEDLINE,Embase,CNKI,VIP,Wan Fang) 中进行全面的文献搜索.
包括在中国批准的基因组向药物的成本效益分析 (2002-2023年).
净货币收益的元分析,用元回归和子组分析来探索异质性.

主要成果:

研究协议概述了合成成本效益数据的方法.
潜在的结果将量化基因组向性瘤药物的经济价值相对于通常的护理.
异质性分析将确定不同癌症类型,阶段和患者人口统计数据中成本效益差异的驱动因素.

结论:

这一系统性审查将为中国精密瘤学的成本效益提供关键证据.
调查结果将为医疗保健政策和针对癌症向治疗的资源分配提供信息.
该研究旨在提高资源有限的环境中先进的癌症治疗方法的可访问性和可持续性.

关键词:

中国中国中国中国.基因治疗是一种基因疗法.医疗保健成本医疗保健成本进行元分析分析.系统审查是系统的审查.

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