在美国成年人中,保留比率受损的螺旋计与脆弱风险之间的关联:一个横截面研究
Li Zhang1,2, Alimire Aierken1, Cuiyi Chen3
1Department of Pulmonary and Critical Care Medicine, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.
BMJ open
|July 17, 2025
概括
保留比率受损螺旋计 (PRISm) 与较高的虚弱风险有关,类似于慢性阻塞性肺病 (COPD). 这一发现强调了需要解决PRISM患者的脆弱性.
科学领域:
- 老年学是指老年学的学科.
- 肺部病理学 肺部病理学
- 流行病学 流行病学
背景情况:
- 脆弱性是老龄化人口日益关注的问题.
- 保持比率损伤螺旋计 (PRISm) 是一种螺旋计模式,通常与呼吸系统疾病有关.
- PRISM与脆弱性之间的关系需要进一步调查.
研究的目的:
- 检查PRISM与脆弱风险之间的关联.
- 为了确定患有PRISm的个体的脆弱性风险因素.
- 为了比较PRISM患者的虚弱风险与COPD患者和正常螺旋计的人.
主要方法:
- 一项采用国家健康和营养检查调查 (2007-2012) 数据的横截面研究.
- 包括6769名年龄在40-85岁之间的参与者,分为PRISm,COPD和非PRISm/COPD组.
- 使用脆弱指数来评估脆弱性,并使用加权后勤回归来进行分析.
主要成果:
- 与非PRISm/COPD组 (13.6%) 相比,PRISm (32.4%) 和COPD (30.4%) 组的脆弱性患病率显著更高.
- 在多变量调整 (OR分别为1.42和1.65) 后,PRISm和COPD都与相似的虚弱风险增加有关.
- 在PRISm患者中发现的脆弱性风险因素包括女性,某些种族/族群,较高的BMI,吸烟,糖尿病和心血管疾病.
结论:
- PRISm与与COPD相似的患病率和脆弱性风险有关.
- 这些发现强调了在被诊断患有PRISm的患者中评估和管理脆弱性的临床意义.
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