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跨支气管冷活检用于诊断扩散性异常性肺神经内分泌细胞增生症 (DIPNECH)

Arista Chand¹, Darius Filsoof², Peter Manchen³

¹Medicine, University of Arizona Medical Center - University Campus, Tucson, Arizona, USA arista.chand@gmail.com.

BMJ case reports

|July 17, 2025

概括

扩散性异常性肺神经内分泌细胞增生 (DIPNECH) 是一种罕见的疾病. 跨支气管肺冷活检 (TBLC) 提供了一种可行且安全的方法来诊断DIPNECH,即使有非特异性症状.

科学领域:

肺部病理学肺部病理学
在瘤学瘤学.
病理学病理学病理学

背景情况:

扩散性异常性肺神经内分泌细胞增生 (DIPNECH) 是一种罕见的疾病.
它被认为是神经内分泌恶性瘤的前体.
由于非特定的临床和放射学发现,诊断具有挑战性.

研究的目的:

介绍一个DIPNECH病例,该病例的诊断方法是使用跨支气管肺冷透镜检查 (TBLC).
突出TBLC作为DIPNECH的可行的诊断工具.

主要方法:

一个患有咳,呼吸障碍和缺氧的女性的案例介绍.
对DIPNECH的组织学确认.
通过跨支气管肺冷活检 (TBLC) 取组织样本.

主要成果:

这位患者最终被诊断为DIPNECH.
TBLC为组织采集提供了一个可行的,安全的替代方案.
通过TBLC获得了组织学确认.

结论:

TBLC是诊断DIPNECH的有效方法.
这种技术有助于对罕见肺病的多学科讨论.
早期诊断DIPNECH对于管理潜在的神经内分泌恶性瘤至关重要.

关键词:

间歇性肺病间歇性肺病呼吸系统药物呼吸系统药物

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