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β-基酸盐通过β-基基化依赖于牛的稳定促进癌症转移

Wenna Jiang1, Meng Wang1,2, Jiayi Wang1

  • 1Department of Clinical Laboratory, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin Key Laboratory of Digestive Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.

Nature communications
|July 17, 2025
PubMed
概括

牛蛋白的β-Hydroxybutyrylation (Kbhb) 通过增强牛的稳定性,促进胰腺癌转移. 针对这种修饰或其酶CBP,可以为胰腺癌提供新的治疗策略.

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