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Updated: Sep 15, 2025

Increased Recovery Time and Decreased LPS Administration to Study the Vagus Nerve Stimulation Mechanisms in Limited Inflammatory Responses
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1型先天性淋巴细胞-未成熟的中性粒细胞轴抑制急性组织炎症

Kenshiro Matsuda1,2,3,4, Natsuki Ide1,5, Yan Xu1,6

  • 1Department of Immunology, Institute of Medicine, University of Tsukuba, Ibaraki, Japan.

Nature communications
|July 17, 2025
PubMed
概括

1型先天性淋巴细胞 (ILC1) 释放干扰素- (IFN-γ) 来调动骨髓中的未成熟中性粒细胞 (imNeu). 这个ILC1-imNeu轴保护组织免受急性炎症和损伤.

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The inflammatory response is the body's defense against infection, injury, or irritation from bacteria, trauma, toxins, or heat. Inflammation helps locate and destroy pathogens and remove damaged tissue elements to heal the body. During this initial phase, fluid, blood products, and nutrients migrate to the injured area, resulting in redness, heat, swelling, ache, and loss of function. Moreover, signs of systemic inflammation include fever, increased WBC count, malaise, anorexia, nausea,...
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