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Gustavo Castro de Lima¹, Janaina de Cassia Orlando Sardi¹, Luciene Cristina de Figueiredo¹

¹School of Dentistry, Guarulhos University UNIVERITAS/UNG, Praça Tereza Cristina, 88 - Centro, Guarulhos, SP, 07023-070, Brazil.

|July 17, 2025

概括

三种S-PRG复合树脂对与牙周炎相关的细菌表现出显著的抗菌活性. 这些生物活性材料有效地减少了多种生物膜,为治疗牙周病提供了有前途的方法.

科学领域:

牙科材料科学牙科材料科学
微生物学微生物学
牙周病学牙周病学

背景情况:

牙周炎与下多种生物膜有关.
复合树脂在恢复性牙科中广泛使用.
生物活性材料提供潜在的治疗益处.

研究的目的:

为了评估S-PRG (含玻璃的S-玻璃离子体) 复合树脂的抗菌功效.
评估这些树脂对牙周炎相关生物膜的微生物特征的影响.
为了比较生物活性树脂与非生物活性对照物的性能.

主要方法:

在体外培养了39种牙周炎生物膜,长达7天.
三种S-PRG复合树脂和一个对照样本被暴露在生物膜中.
使用DNA-DNA杂交和色度测试分析了生物膜组成,代谢活性和微生物特征.

主要成果:

生物活性S-PRG复合树脂显著降低了关键周期性病原菌的数量.
黄色和色细菌复合物的比例有显著的下降.
与对照组相比,在存在S-PRG树脂的情况下,生物膜中的总细菌数量显著下降.

结论:

将S-PRG玻璃融入复合树脂中有效地抑制了周期性病原体生物膜的生长.
生物活性复合树脂在牙周病管理中显示出降低细菌负载的潜力.
S-PRG复合树脂代表了在牙周损伤患者的修复应用的有希望的材料.

关键词:

抗微生物活性的抗菌活性.生物活性生物活性生物膜是一种生物膜.复合树脂是一种复合树脂.在 S-PRG 填充剂中使用 S-PRG 填充剂

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Biofilms

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