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Updated: Sep 15, 2025

Stencil Micropatterning of Human Pluripotent Stem Cells for Probing Spatial Organization of Differentiation Fates
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为什么印记在多能干细胞中不稳定?

Maria Arez1,2, Simão Teixeira da Rocha1,2

  • 1Department of Bioengineering, iBB - Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.

Biochemical Society transactions
|July 18, 2025
PubMed
概括

多能干细胞 (PSC) 对于研究至关重要,但容易发生表观遗传错误,如基因组印记缺陷. 这些错误通过差异化持续存在,影响PSC治疗用途的安全性和可靠性.

关键词:
通过DNA甲基化.表观遗传学是指表观遗传学.基因组印记是基因组的印记.多能性的多能性.干细胞是干细胞的组成部分.

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