耐力运动对认知功能,神经变因子,大脑结构和老年人大脑功能的影响:叙述性综述
Wanting Jiang1, Xing Wang1, Lijuan Mao1
1School of Athletic Performance, Shanghai University of Sport, Shanghai, China.
Journal of Alzheimer's disease : JAD
|July 18, 2025
概括
阻力运动 (RE) 显示了增强认知功能,如老年人的记忆和执行功能. 需要进一步的研究来优化RE参数,以获得最大的认知和大脑健康益处.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 运动科学 运动科学
背景情况:
- 认知能力下降是老年人群的一个重大问题,通常与痴呆症和阿尔茨海默病 (AD) 相关.
- 有氧运动 (AE) 对认知益处进行了充分研究,但在运动认知研究中,抵抗运动 (RE) 仍未得到充分探索.
- 了解RE的影响对于开发有效的策略来支持老年人认知健康至关重要.
研究的目的:
- 审查抗力运动 (RE) 对老年人认知功能的影响.
- 检查RE参数如何影响认知结果.
- 探索RE诱导的神经营养因子,大脑结构和功能的适应,以及它们与认知改善的联系.
主要方法:
- 一个叙述性综述,综合了随机对照试验 (RCT) 的证据.
- 在PubMed数据库中进行全面的文献搜索,截至2025年1月.
- 包括41个研究耐力运动和老年人认知功能的RCT.
主要成果:
- 耐力运动 (RE) 显示出改善老年人执行功能,记忆和全球认知能力的潜力,包括那些认知障碍者.
- 有证据表明,RE可能会增加外围胰岛素样生长因子1 (IGF-1) 的水平.
- RE与增加灰质厚度,减少海马缩以及增强大脑活化有关,与认知收益相关.
结论:
- 抵抗运动 (RE) 是一种可行的干预措施,可以提高老年人群的认知和大脑健康.
- 最佳的RE参数 (强度,频率,持续时间) 需要进一步调查.
- 经RE介导的神经生物学适应似乎支了认知改善,突出了其治疗潜力.
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