基于机器学习的肺癌诊断研究
Haihui Huang1, Aitong Zhong1, Decheng Miao1
1Provincial Demonstration Software Institute, Shaoguan University, Shaoguan, China.
概括
机器学习模型有效地将肺组织分类为良性或恶性,并评估癌症的攻击性. 混合L1/2 + L2规范化 (HLR) 达到96.67%的准确率,而人工神经网络 (ANN) 达到91.82%的准确率.
科学领域:
- 计算生物学是一种计算生物学.
- 医疗信息学医学信息学
- 机器学习在瘤学中
背景情况:
- 准确的瘤分类对于有效的癌症治疗至关重要.
- 区分良性瘤和恶性瘤是一个重大的诊断挑战.
- 机器学习为改善诊断准确性和速度提供了潜在的解决方案.
研究的目的:
- 评估机器学习方法来将肺组织分类为良性或恶性.
- 评估各种算法的性能,以确定肺癌的攻击性.
- 为了比较用于肺癌诊断的内置特征选择和没有内置特征选择的方法.
主要方法:
- 采用人工神经网络 (ANN) 和物流回归变体.
- 在没有内置特征选择的情况下使用的方法:ANN,后勤回归,峰处罚后勤回归.
- 使用内置特征选择的应用方法:拉索惩罚后勤回归,弹性网惩罚后勤回归和混合L1/2 + L2规范化 (HLR).
主要成果:
- 在分类良性/恶性肺组织 (没有特征选择) 中,ANN获得了91.82%的准确性.
- 在分类良性/恶性肺组织 (具有特征选择) 中,HLR实现了96.67%的准确性.
- 在评估肺癌的攻击性 (没有特征选择) 中,ANN的准确率达到了84.74%.
- 在评估肺癌的攻击性 (具有特征选择) 中,HLR达到93.33%的准确性.
结论:
- 在整合特征选择时,HLR在分类肺组织和评估癌症攻击性方面表现出卓越的表现.
- 在没有内置特征选择的方法中,ANN在两种分类任务中都表现出强大的竞争力.
- 无论是HLR还是ANN,都显示出改善肺癌诊断和分级的巨大潜力.
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