使用媒体来增强儿童患者招募用于初级保健研究的机会
Ilse N Ganzevoort1, Marjolein Y Berger1, Marc A Benninga2
1Department of Primary and Long-term Care, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Primary health care research & development
|July 18, 2025
概括
媒体招募有效地招募儿童进行初级保健研究,没有显著的基线差异. 这种方法可以减少临床试验参与者招聘的全科医生 (GPs) 的负担.
科学领域:
- 儿科研究 儿科研究
- 主要护理医学 医疗保健
- 临床试验招聘 临床试验招聘
背景情况:
- 在初级保健机构招募儿科参与者进行研究具有重大挑战.
- 不良的参与者招募可能导致随机对照试验 (RCT) 的延迟或终止.
研究的目的:
- 通过媒体招募的儿童与全科医生 (GPs) 的特征进行比较.
- 评估不同招聘策略对儿科功能性腹痛 (FAP) 和刺激性肠综合征 (IBS) 研究中的参与者人口统计和临床资料的影响.
主要方法:
- 对152名患有FAP或IBS的儿童 (7-17岁) 的比较分析.
- 根据招聘来源 (媒体与GP) 评估人口统计,临床和心理社会特征.
主要成果:
- 两组招募人群之间没有观察到临床上显著的基线差异.
- 通过媒体招募的儿童表现出更长的症状持续时间和更高的FAP诊断的患病率,与那些被全科医生招募的儿童相比.
结论:
- 媒体招募是招募儿童参加初级保健研究的有效策略,而不会引入重大基线差异.
- 利用媒体进行招聘可能会减轻全科医生的招聘负担.
- 建议进行进一步的子组分析,以探索潜在的未知基线差异,受招聘方法的影响.
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