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长时间睡眠时间与心血管复发的增加有关:从CORDIOPREV研究中长期地中海饮食的影响
Antonio García-Ríos1,2, Juan Luis Romero-Cabrera1,2, Juan Francisco Alcalá-Díaz1,2
1Lipids and Atherosclerosis Unit, Maimonides Institute for Biomedical Research in Cordoba (IMIBIC), Reina Sofia University Hospital, University of Córdoba, Córdoba, Spain.
Journal of internal medicine
|July 18, 2025
概括
较长的睡眠时间增加了冠心病患者主要心血管事件 (MACE) 的风险. 地中海饮食可能有助于降低这种风险,强调睡眠.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 营养科学 营养科学
背景情况:
- 睡眠模式和饮食之间的相互作用影响冠心病 (CHD) 风险.
- 调查睡眠时间对重大心血管不良事件 (MACE) 的影响对于预防心血管疾病至关重要.
- 科迪奥普雷夫研究提供了一个平台,与睡眠时间一起检查饮食干预措施.
研究的目的:
- 为了评估睡眠时间和MACE发病率在心脏病患者之间的关联.
- 评估地中海饮食与低脂肪饮食对这种关联的影响.
主要方法:
- 952名参与者被分为睡眠时间短 (≤6小时),参考 (>6至<8小时) 和长 (≥8小时) 的睡眠时间组.
- 睡眠时间是自报告使用明尼苏达州休时间体育活动调查问卷超过7年.
- MACE包括心肌梗塞,再血管,缺血性中风,外周动脉疾病和心血管死亡率.
主要成果:
- 长时间睡眠时间 (≥8h) 与MACE风险显著增加有关 (HR: 1.59).
- 在睡眠时间长的参与者中,低脂肪饮食增加了MACE风险 (HR: 1.74).
- 地中海饮食没有显示长时间睡眠者MACE风险显著增加 (HR:1.35).
结论:
- 长时间的睡眠时间是MACE在心血管疾病患者的独立风险因素.
- 坚持地中海饮食可能会减轻与长时间睡眠相关的心血管风险.
- 在临床实践中,睡眠时间应被视为可修改的心血管风险因素.
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