在自闭症谱系障碍中药物治疗的数据集
Sebastião Gonçalves de Barros Neto1, Catherine Oliveira de Araújo1, Renandro de Carvaho Reis2
1Laboratory of Neurobiology, Mackenzie Presbyterian University. Rua da Consolação, 930 - prédio 28, 10 andar - São Paulo- SP, CEP 04048061, Brazil.
Data in brief
|July 18, 2025
概括
在患有自闭症谱系障碍 (ASD) 的儿童中,精神药物使用很常见,特别是在较低的社会经济群体中. 较高的ASD严重程度,和年龄与增加的药物使用相关.
科学领域:
- 神经科学是一个神经科学.
- 发育儿科 发育儿科
- 心理药理学 心理药理学
背景情况:
- 药理干预经常用于管理与自闭症谱系障碍 (ASD) 相关的症状.
- 了解不同人群的药物使用模式,包括那些社会经济地位较低的人群,对于公平的医疗保健至关重要.
- 之前的研究还没有在巴西的低收入自闭症患者中详细介绍精神药物特征.
研究的目的:
- 调查一组被诊断患有自闭症谱系障碍 (ASD) 的来自巴西圣保罗市Embu das Artes低社会经济阶层的儿童的精神药物使用情况.
- 在这个特定的人群中,确定与精神药物使用相关的因素,包括药物类型和多药.
- 为未来关于合理药物使用和ASD儿童不良影响监测的研究提供数据.
主要方法:
- 一项涉及129名自闭症儿童的横截面研究,来自巴西圣保罗市Embu das Artes的公立学校.
- 数据收集包括临床评估和父母报告的药物使用问卷.
- 评估了社会经济地位,自闭症严重程度,并发症 (例如) 和年龄.
主要成果:
- 超过一半 (57.36%) 的自闭症儿童正在接受心理药物干预,其中33.78%接受多药.
- 典型抗精神病药物 (35.4%) 是最常见的,其次是非典型抗精神病药物 (27.43%),抗发作药物 (19.47%) 和三环抗抑郁药 (7.08%).
- 更高的ASD严重程度 (2和3级),和年龄较大与增加的精神药物使用有显著的关联.
结论:
- 包括多药在内的精神药物使用在巴西社会经济水平较低的样本中,在ASD儿童中很普遍.
- 特定的临床因素,如自闭症严重程度,和年龄影响药物处方模式.
- 这项研究强调,需要仔细监测药物使用情况以及这种脆弱人群中潜在的不良影响.
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