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绘制未来:角膜上皮厚度的前部段 OCT 在春季角膜结膜炎

Swarastra Prakash Singh¹, Ruchi Shukla², Pragati Garg³

¹Additional Professor, Department of Ophthalmology, All India Institute of Medical Sciences, Raebareli, Uttar Pradesh, India.

|July 18, 2025

概括

患有春季角膜结膜炎 (VKC) 的儿童显示角膜表皮较薄,特别是在上方象限. 前段光学连贯断层扫描 (OCT) 对于监测这些与VKC相关的角膜变化至关重要.

科学领域:

眼科医生眼科眼科
角质科学角质科学
儿科眼部疾病儿科眼部疾病

背景情况:

春季角膜结膜炎 (VKC) 是一种双边,发,季节性眼睛炎症.
在VKC中角膜的参与可以导致显著的视力损伤.
需要使用非侵入性成像技术来评估儿科VKC的角膜变化.

研究的目的:

为了比较患有VKC和健康对照儿童之间的角膜上皮的参数.
评估前段光学连贯性断层扫描 (OCT) 在评估与VKC相关的角膜变化的实用性.

主要方法:

前段OCT用于测量中部5毫米角膜的上皮质厚度.
这项研究包括了108只VKC患者的眼睛和108只健康对照的眼睛 (5-18岁).
对角膜上皮质厚度参数进行了分析,并在各组之间进行了比较.

主要成果:

与对照组相比,患有VKC的儿童表现出明显较薄的上角膜上皮质 (38.69 ± 5.91 μm vs 40.98 ± 3.86 μm).
在VKC患者中,表皮体最小厚度降低,MIN-MAX值更高.
混合的VKC病例显示上层上皮质稀薄和最小上皮质厚度降低.

结论:

患有VKC的儿童有显著的角膜上皮质厚度变化,特别是上部和最小厚度显著减少.
长时间的VKC持续时间与上皮质稀薄的增加相关.
前段OCT是跟踪儿科VKC角膜变化的一个有价值的工具.

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