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从总结统计数据直接计算遗传风险得分,并对1型糖尿病进行应用

Steven Squires1, Michael N Weedon1, Richard A Oram1,2

  • 1Clinical and Biomedical Sciences, University of Exeter, St Luke's Campus, Exeter, EX1 2LU, United Kingdom.

Bioinformatics advances
|July 18, 2025
PubMed
概括

现在只能使用总结统计数据来计算遗传风险得分 (GRS),从而可以在数据集之间进行更广泛的比较. 这种用于GRS开发的方法显示了与使用原始遗传数据相比的性能.

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