平衡检测可见光学连贯断层扫描用低噪音超连续激光.
Lucy Abbott1, Gianni Nteroli1,2, Rasmus D Engelsholm3
1Applied Optics Group, School of Engineering, Mathematics and Physics, University of Kent, CT2 7NH, Canterbury, United Kingdom.
Biomedical optics express
|July 18, 2025
概括
平衡检测显著改善可见光学连贯断层扫描 (OCT) 成像. 该技术使用低噪音超连续激光和数字像素对齐,减少噪音,提高图像灵敏度和对比度.
科学领域:
- 生物医学光学 生物医学光学
- 光学成像技术的成像
- 干涉测量是干涉测量的方法.
背景情况:
- 光学连贯断层扫描 (OCT) 是一种有价值的非侵入性成像方式.
- 提高灵敏度和降低噪音对于改善海外国家和地区的图像质量至关重要.
- 可见光OCT为表面组织成像提供了潜力.
研究的目的:
- 为了证明在可见的OCT系统中平衡检测的效率.
- 为了展示降低噪音和提高灵敏度.
- 用幻影和体内成像来验证性能.
主要方法:
- 使用可见的OCT仪器与低噪音超连续激光.
- 实施了一种用于摄像头校准的新型数字像素对齐技术.
- 采用平衡检测配置以尽量减少噪音.
- 在590nm的中心波长下运行.
主要成果:
- 在成像深度范围内实现了高达12.8dB的噪声底部降低.
- 经过证明的高灵敏度:74dB (单个光谱仪) 和92.8dB (平衡配置).
- 在光学幻影和in-vivo人类指/指甲图像中呈现了增强的图像对比度.
结论:
- 均衡检测对于提高可见的OCT性能非常有效.
- 开发的数字对齐技术显著改善了降噪.
- 该系统提供高分辨率,高灵敏度成像,用于表面组织可视化.
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