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被治疗的视网母细胞瘤眼睛的折射参数
Hany Anwar Abdallah1, Momen Mahmoud Hamdi1, Sameh Hany Abdel Rahman1
1Department of Ophthalmology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Ocular oncology and pathology
|July 18, 2025
概括
与健康的眼睛相比,经过治疗的视网膜母细胞瘤眼睛显示了折射参数的显著变化,包括增加了纹和较浅的前腔室. 视网膜母细胞瘤患者的同伴眼睛与健康对照人群没有区别,这表明疾病治疗的局部效应.
科学领域:
- 眼科医生 眼科 眼科
- 儿科瘤学 儿科瘤学
- 折射误差研究 折射误差研究
背景情况:
- 视网母细胞瘤是儿童常见的眼内恶性瘤.
- 视网母细胞瘤的治疗可能导致长期的眼部并发症.
- 了解治疗后的折射变化对于视觉康复至关重要.
研究的目的:
- 为了研究治疗的视网母细胞瘤对眼睛折射参数的影响.
- 为了比较治疗视网膜母细胞瘤眼睛的折射结果,与同眼睛和健康对照进行比较.
主要方法:
- 病例对照研究比较治疗视网膜母细胞瘤眼睛 (n=35),同眼睛 (n=25) 和健康对照 (n=26).
- 使用循环折射,眼部生物识别和前段光学连贯性断层扫描.
- 图像J软件校准了镜头表面曲率.
主要成果:
- 与健康对照人群相比,接受治疗的视网膜母细胞瘤眼睛表现出显著更高的折射性光学 (p=0.02) 和角膜光学 (p=0.047).
- 前腔深度显著较浅 (p<0.001),后镜片曲率更圆 (p=0.041) 在接受治疗的视网膜母细胞瘤眼睛与健康对照.
- 在接受治疗的视网膜母细胞瘤眼睛和同类眼睛 (p<0.001) 之间,在折射性和角膜白症中发现了显著的差异.
结论:
- 被治疗的视网母细胞瘤眼睛呈现出明显的折射特征,包括增加的光学和改变的角膜和透镜形状.
- 这些折射变化归因于治疗的疾病,而不是遗传倾向,因为同眼睛与健康对照没有区别.
- 这些发现强调了需要在接受视网膜母细胞瘤治疗的儿童中进行专门的折射性治疗.
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