持续的机械吸收血栓切除术急性冠状动脉综合征与大血栓负担:吸收,血管扩张器,成像和支架 (AVIS) 协议
Tanuj Bhatia1, Aditya Kapoor2, Vishal Rastogi3
1Professor & Head, Department of Cardiology, SGRR Medical College & SMI Hospital, Dehradun, Uttarakhand, India.
概括
持续的机械吸血血栓切除术有效地清除了急性冠状动脉综合征患者的大型血栓负担中的血栓. 这种干预改善了心肌输液和左心室功能,表明其在临床实践中的价值.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 带有大血栓负担 (LTB) 的急性冠状动脉综合征 (ACS) 对再注血提出了重大挑战.
- 穿皮冠状动脉干预 (PCI) 单独可能在LTB病例中不足.
研究的目的:
- 评估前期持续机械吸血血栓切除术在LTB的ACS患者中使用IndigoTM系统的有效性和安全性.
- 评估对血栓溶解,心肌 perfusion 和临床结果的影响.
主要方法:
- 一项前性观察性研究,涉及105名患有LTB的ACS患者,接受初级PCI.
- 在初级PCI之前,使用IndigoTM系统CATTM RX进行前部机械吸血血栓切除术.
- 在心肌梗塞 (TIMI) 流量中对血栓溶解的评估,TIMI血栓等级和心肌红色度 (MBG) 在基线和术后.
主要成果:
- 在TIMI流量,TIMI血栓等级和血栓切除术后的MBG中观察到显著的改善 (p < 0.001).
- 平均左心室喷射分数从基线时的38.37%增加到6个月后的44.63% (p < 0.001).
- 与设备相关的不良事件发生率低;30天内有3起与设备无关的死亡.
结论:
- 持续的机械吸收血栓切除术在去除血块和改善心肌输液方面是有效的,在患有LTB的ACS患者中.
- 建议采用吸收,血管扩张,成像,支架 (AVIS) 协议,以进一步提高程序的成功.
- 这种技术为主PCI提供了有价值的辅助,用于在ACS中管理LTB.
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