相对脂肪质量和骨矿物质密度之间的负相关性:NHANES 2011-2018年
Xing-An Jiang1,2, Hong-Li Zhang3, Bin-Tao Ye3
1Department of Orthopedic, Taizhou Hospital Affiliated to Zhejiang University School of Medicine, Taizhou, China.
Frontiers in public health
|July 18, 2025
概括
较高的相对脂肪质量 (RFM) 与成人下腰部骨矿物质密度 (BMD) 有关. 这种反向关系表明RFM可能表明骨质疏松症风险,并告知早期干预.
科学领域:
- 内分泌学 在内分泌学.
- 骨的新陈代谢 骨的新陈代谢
- 公共卫生 公共卫生
背景情况:
- 国家健康和营养检查调查 (NHANES) 提供有关成人健康的数据.
- 了解影响骨矿物质密度 (BMD) 的因素对于公众健康至关重要.
- 相对脂肪量 (RFM) 是肥胖的一个新兴指标.
研究的目的:
- 调查成年人相对脂肪量 (RFM) 和腰椎骨矿物质密度 (BMD) 之间的关联.
- 评估RFM对腰部BMD的影响.
- 为了确定这种关系是否在不同的人口中有所不同.
主要方法:
- 来自NHANES 2011-2018周期的9,238名成年人 (年龄≥20岁) 的横截面数据的分析.
- 使用腰围和高度计算RFM.
- 通过加权多重线性回归和子组分析评估RFM-BMD关系.
主要成果:
- 在RFM和腰椎BMD之间发现了统计学上显著的反向关系.
- 每个单位的RFM增加都与腰部BMD下降0.0110g/cm2有关 (p < 0.0001).
- 在RFM=20.5847的拐点表明了在这个值以上和以下的不同相关性,在各个子组中一致.
结论:
- 升高的RFM与腰椎骨质量减少有关,可能增加骨质疏松症风险.
- RFM可以作为早期临床干预措施的指标,以防止骨密度下降.
- 通过RFM评估的脂肪分布模式对于骨质疏松症预防策略很重要.
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