美国成年人的身体圆度指数,甲状腺激素和值效应:NHANES的横截面研究
Sijia Yang1, Kun Liao2, Lu Zhou3
1Department of Thyroid Diagnosis and Treatment Center, Zhuhai People's Hospital (The Affiliated Hospital of Beijing Institute of Technology, Zhuhai Clinical Medical College of Jinan University, Zhuhai, China.
Frontiers in nutrition
|July 18, 2025
概括
身体圆度指数 (BRI) 显示了对甲状腺激素的非线性影响,如总三甲状腺素 (TT3) 和总甲状腺素 (TT4). 用BRI测量的内脏脂肪分布会影响甲状腺激素水平,特别是在一定值之后.
科学领域:
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
- 身体组成分析 身体成分分析
背景情况:
- 传统的身体质量指数 (BMI) 在评估内脏脂肪组织分布方面是有限的.
- 内脏脂肪和甲状腺激素之间的关系需要进一步研究.
- 身体圆度指数 (BRI) 提供了一个用于评估内脏脂肪的几何度量.
研究的目的:
- 为了研究BRI和甲状腺激素水平之间的非线性关系.
- 为了确定BRI对甲状腺激素度的潜在值影响.
- 探索美国人口内脏脂肪分布和甲状腺功能之间的关联.
主要方法:
- 在国家健康和营养检查调查 (NHANES) (2007-2012) 中,从10,086名参与者的横截面数据分析.
- 对人类测量和甲状腺激素水平 (FT3,TT3,FT4,TT4,TSH) 的评估.
- 应用多种线性和分片回归模型来检查BRI与甲状腺激素的关联,包括非线性和值效应.
主要成果:
- 在BRI和总三甲状腺素 (TT3) 和总甲状腺素 (TT4) 之间观察到正相关性.
- 在BRI和自由甲状腺素 (FT4) 之间发现了负相关性.
- 值分析表明,BRI会影响自由三甲状腺素 (FT3) 和TT3,其影响会超过7.21的BRI.
结论:
- BRI与美国人口中甲状腺激素水平的非线性关系和值效应有关.
- 根据BRI的指示,内脏脂肪分布与TT3/TT4正相关,与FT4.4负相关.
- BRI对FT3和TSH的动态值效应强调了在甲状腺激素评估中考虑内脏脂肪分布的重要性.
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