短身高对早产的影响:一项回顾性队列研究
Joan Crane1, Phil Murphy2, Donnette O'Brien2
1Department of Obstetrics and Gynecology, Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada.
概括
低身高的母亲与早产有关,风险因体重指数 (BMI) 和出生类型而异. 体重指数正常,身材矮小的母亲面临更高的自发早产风险,而超重/肥胖的母亲面临更高的预示早产风险.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 公共卫生 公共卫生
背景情况:
- 孕产妇的身高是妊娠结果的潜在决定因素.
- 母体身高和早产之间的关系可能会受到体重指数 (BMI) 和特定类型的早产的影响.
研究的目的:
- 调查母亲身高矮与早产之间的关联.
- 探索这种关联是如何通过不同的身体质量指数 (BMI) 类和早产类型 (自发与指示) 来改变的.
主要方法:
- 在加拿大纽芬兰和拉布拉多 (Newfoundland and Labrador,加拿大) (2012-2019) 的16023例单独怀孕的回顾性队列研究 (2012-2019).
- 母亲身高分类为矮 (<25%),平均 (25%-75%) 和高 (>75%).
- 使用回归分析来评估由矮身对早产的独立预测,按BMI和出生类型分层.
主要成果:
- 在所有BMI类别 (或1.37) 中,母亲的矮身独立预测过早分娩.
- 在正常的BMI个体中,矮身高预测了早产 (OR 1.52);这种关联在超重 (OR 1.52) 和肥胖 (OR 1.32) 组中持续存在.
- 低身高与正常体重指数女性的自发早产有关 (OR 1.59) 和超重/肥胖女性的早产有关 (OR 1.60).
结论:
- 低身高对早产的影响取决于母亲的BMI和早产的机制.
- 矮身与正常BMI的女性的自发早产有关.
- 矮身与超重或肥胖妇女预先分娩的风险增加有关.
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