反边噪声对皮质听力引起的潜在延迟和振幅的影响
Donguk Lee1, James D Lewis2, Ashley Harkrider3
1Department of Audiology and Speech Pathology, University of North Texas, Denton.
概括
中间橄耳反射 (MOCR) 增强了神经对人类声音的反应,如晚期延迟反应 (LLR) 所示. 这项研究证明了使用LLR在神经水平上使用MOCR介导的揭示.
科学领域:
- 听觉神经科学 听觉神经科学
- 神经科学是一个神经科学.
- 耳声波排放 耳声波排放 耳声波排放
背景情况:
- 众所周知,中枢橄耳反射 (MOCR) 在动物中调节神经信号噪声比 (SNR),这种现象被称为揭示.
- 人类中MOCR介导的揭示的证据有限,部分原因是依赖神经前耳声排放 (OAE).
- 晚期延迟反应 (LLR) 对SNR变化敏感,并提供了MOCR揭露的潜在的非侵入性神经测量方法.
研究的目的:
- 为了研究MOCR介导的人类ipsilateral噪声的增强.
- 评估LLRs在评估神经水平上MOCR揭示的实用性.
主要方法:
- 五十个正常听觉的成年人参与了.
- 在静音和噪音下,在不同SNR (+5, +15, +25dB),有或没有反侧噪声的情况下,记录了1kHz的LLR.
- 测量了耳声排放 (OAEs),以比较神经和神经前反应.
主要成果:
- 随着SNR的改善,LLR的延迟时间减少,幅度增加.
- 反边噪声显著降低了P1和N1延迟,并增加了LLR间峰幅度.
- 虽然OAE与反侧面噪声减少,但与LLR变化的显著相关性并未始终被发现.
结论:
- 反侧边噪声呈现似乎增强神经对人体ipsilateral噪声的反应.
- 这种增强很可能是通过中间橄耳耳系统的介导.
- 在人类中,LLRs提供了一个可行的神经测量方法来研究MOCR揭示.
相关概念视频
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