饮食习惯和肝细胞癌 - - 对临床实践的潜在影响
Chloé Matray1, Charlotte Debras2, Anastasia Chrysovalantou Chatziioannou2,3
1Department of Gastroenterology, Military Hospital Percy, Clamart 92140, France.
Nutrition reviews
|July 18, 2025
概括
饮食习惯显著影响肝癌 (HCC) 风险,西方饮食增加风险,植物性食物可能减少风险. 营养干预是预防的关键,特别是在与代谢功能障碍相关的脂肪性肝病 (MASLD) 患者中.
科学领域:
- 肝病学和瘤学研究专注于代谢疾病.
- 调查饮食对肝癌发生的影响.
背景情况:
- 肥胖和MASLD等代谢障碍是导致肝癌 (HCC) 的原因.
- 西方的饮食模式和久坐不动的生活方式有助于全球代谢疾病流行.
- 特定饮食习惯在调节HCC风险中的作用需要进一步研究.
研究的目的:
- 综合审查饮食成分与HCC风险之间的联系.
- 确定肝癌的已确定的和潜在的饮食风险因素.
主要方法:
- 系统审查国际癌症研究机构的专著和WCRF/AICR报告.
- 在PubMed数据库中搜索有关食品和HCC的系统审查和元分析.
- 对饮食成分,污染物及其与肝癌风险相关性的分析.
主要成果:
- 摄入大量的红肉/加工肉,和脂肪和高血糖负载的食物与增加的HCC风险相关.
- 西方饮食可能通过元炎症,胰岛素耐药性和肠道微生物群变化促进肝癌.
- 增加蔬菜,豆类,水果和全谷物的消费可能会对HCC产生保护作用.
结论:
- 促进健康的饮食习惯是减少HCC风险的可行的长期策略.
- 患有MASLD且没有晚期纤维化症的患者是HCC预防策略的关键人群.
更多相关视频
09:15Vinyl Chloride and High-Fat Diet as a Model of Environment and Obesity Interaction
Published on: January 12, 2020
6.5K
09:27Analysis of Liver Microenvironment During Early Progression of Non-Alcoholic Fatty Liver Disease-Associated Hepatocellular Carcinoma in Zebrafish
Published on: April 1, 2021
3.6K
相关概念视频
Hepatic Drug Excretion: Influencing Factors
227
The biliary system of the liver, crucial for bile secretion and drug excretion, comprises intrahepatic bile ducts that merge to form the common hepatic duct. This duct, carrying hepatic bile, combines with the cystic duct, draining the gallbladder and forming the common bile duct, which empties into the duodenum. Bile, produced by hepatic cells lining the bile canaliculi, is composed primarily of water, bile salts, pigments, electrolytes, and lesser amounts of cholesterol and fatty acids. Bile...
227
Diseases of the Liver and Gallbladder
1.0K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
1.0K
Cancer Prevention
6.3K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.3K
Liver Physiology
1.3K
The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
1.3K
