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Updated: Sep 14, 2025

A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4
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DPP4和FcRn作为Caco-2细胞中古典人类天体病毒的受体和共受体的功能性表征

Catalina Aguilera-Flores1, María Del Pilar Valencia-Morales1, Tomás López1

  • 1Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, Mexico.

PLoS pathogens
|July 18, 2025
PubMed
概括

双基酶IV (DPP4) 作为人类天体病毒 (HAstV) 的主要受体,而新生儿Fc受体 (FcRn) 作为核心受体. 这些相互作用对于病毒进入和基因组释放至关重要,为抗病毒开发提供了点.

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