人类乳头瘤病毒疫苗接种覆盖率和中国大陆妇女的意愿:基于COM-B模型的元分析
Tingsu Tao1, Yajuan Ni1, Naiyang Shi1
1Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210009, China.
Vaccine
|July 18, 2025
概括
在中国,人乳头瘤病毒 (HPV) 疫苗接种覆盖率很低,为9.5%,尽管愿意接种很高 (70.6%). 能力,机会和动机等因素影响吸收,社会和知识因素起着关键作用.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 疫苗学 疫苗学 疫苗学
背景情况:
- 中国大陆的人类乳头瘤病毒 (HPV) 疫苗接种覆盖率较低,需要了解影响因素.
- 行为能力,机会和动机模型 (COM-B) 为分析健康行为提供了一个框架.
研究的目的:
- 估计中国大陆妇女的HPV疫苗接种覆盖率和意愿.
- 使用COM-B模型识别影响HPV疫苗接种的因素.
主要方法:
- 一个系统的审查和对155项涉及1000多万妇女的研究进行元分析.
- 使用随机效应模型计算了聚合HPV疫苗接种覆盖率和意愿.
- 用子组分析,元回归和COM-B模型来确定影响因素.
主要成果:
- 聚合HPV疫苗接种覆盖率为9.5% (95%CI:7.6%-11.6%),接受查的妇女 (16.9%) 和医疗保健工作者 (13.4%) 的比例更高.
- 接种疫苗的意愿明显高于70.6% (95%CI:66.8%-74.3%).
- 在COM-B模型中,能力,机会和动机方面显著影响了覆盖率和愿意度,能力与覆盖率的相关性最强 (OR=2.96).
结论:
- 在中国大陆妇女的HPV疫苗接种意愿和实际覆盖率之间存在很大的差距.
- 接种疫苗的家人或朋友以及对HPV及其疫苗的了解与更高的疫苗接种率有关.
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