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Updated: Sep 14, 2025

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缺少Sfrp2的结肠纤维细胞在性结肠炎中驱动粘膜炎和上皮损伤

Mengyuan Zhu1, Zhanqiu Diao2, Lei Hu3

  • 1Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, Beijing Stomatological Hospital, School of Stomatology, Capital Medical University, Beijing, China; Department of Dental Emergency, Beijing Stomatological Hospital, School of Stomatology, Capital Medical University, Beijing, China.

Cellular immunology
|July 18, 2025
PubMed
概括

在肠道纤维细胞中分泌的状相关蛋白2 (SFRP2) 能够防止性结肠炎 (UC) 的严重程度. 纤维细胞中SFRP2的损失通过促进炎症T细胞反应加剧UC.

关键词:
纤维细胞细胞.炎症 炎症是一种炎症.粘膜免疫力 粘膜免疫力分泌的纹相关蛋白2 (SFRP2)性结肠炎是一种

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