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埃博拉病毒矩阵蛋白VP40的变体对寡合化和血相互作用有不同的影响

Balindile B Motsa1, Barsha Bhowal1, Yogesh B Narkhede2

  • 1Borch Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue Institute of Inflammation, Immunology, and Infectious Disease, Purdue University, West Lafayette, Indiana, USA.

The Journal of biological chemistry
|July 18, 2025
PubMed
概括

研究了两个埃博拉病毒矩阵蛋白VP40突变. R204H破坏了VP40s的功能,而H269R增强了它与宿主细胞膜的相互作用,影响了埃博拉病毒组装.

关键词:
埃博拉病毒埃博拉病毒.在 VP40 中,VP40 是 VP40 的.静电学 静电学 静电学脂质蛋白相互作用 脂质蛋白相互作用酸氨基酸-4,5-双酸盐是一种酸盐酸氨酸的含量是多少血膜是一种等离子体膜.病毒组装组合的病毒组合.病毒的芽 病毒的芽

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