心血管健康,根据生命的基本8项,以及老年人下肢功能受损
David Gómez-Ángel1, Mercedes Sotos-Prieto1,2,3,4, David Martínez-Gómez1,2,4
1Department of Preventive Medicine and Public Health, Universidad Autónoma de Madrid, Madrid, Spain.
Aging and disease
|July 18, 2025
概括
保持良好的心血管健康 (CVH) 与老年人较好的下肢功能有关. 改善美国心脏协会的生命必需8 (LE8) 评分可以降低下肢功能受损 (ILEF) 的风险.
科学领域:
- 老年学是指老年学的学科.
- 心血管健康 心血管健康
- 生物医学科学 生物医学科学
背景情况:
- 心血管健康 (CVH) 对整体健康至关重要,但其对老年人下肢功能的影响尚不清楚.
- 下肢功能障碍 (ILEF) 是导致老年人残疾,生活质量下降和死亡的重要因素.
研究的目的:
- 在65岁及以上的个人中,研究心血管健康和下肢功能之间的横截面和前性关联.
- 为了确定较高的心血管健康评分是否预测随着时间的推移,下肢功能受损的流行率和发病率较低.
主要方法:
- 利用了来自老年人-ENRICA-2队列 (年龄≥65岁) 2,487名参与者的数据.
- 评估CVH使用美国心脏协会的Life's Essential 8 (LE8) 评分和通过短物理性能电池 (SPPB) 的下肢功能在基线和随访 (2.4年和5.2年).
- 采用后勤回归分析,根据关键混因素进行调整.
主要成果:
- 在LE8得分增加10个点与ILEF在基线发病率较低 (OR0.75) 和在2.4年 (OR0.77) 和5.2年 (OR0.76) 期间发生ILEF风险降低有关.
- 这种关联的关键因素包括身体活动,葡萄糖水平,体重指数和尼古丁暴露.
- 较高的CVH,如LE8得分所示,与老年人较好的下肢功能有显著的联系.
结论:
- 较高的心血管健康评分与老年人下肢功能受损的患病率和发病率较低有关.
- 对CVH的全面评估为下肢功能的进展提供了有价值的见解,并确定了早期干预的潜在目标.
- 促进心血管健康是维持老年人群的流动性和功能的一个有希望的策略.
相关概念视频
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