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Updated: Sep 14, 2025

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葡萄糖皮质体受体调节器的设计和开发

Frank Buttgereit1, Christian Elling2, Florian Jakob3

  • 1Department of Rheumatology and Clinical Immunology, Charité Universitätsmedizin Berlin, and Deutsches Rheumaforschungszentrum, Berlin, Germany.

Trends in pharmacological sciences
|July 18, 2025
PubMed
概括

合成葡萄糖皮质类药物 (GCs) 减少炎症,但引起副作用. 新的药物称为葡萄糖皮质体受体调节剂 (GRMs) 正在开发,以向特定的基因通路,提供更安全的抗炎方法.

关键词:
这就是SEGRAMs.葡萄糖皮质类受体的受体.葡萄糖皮质类药物是什么非类固醇葡萄糖皮质体受体调节器转录激活的转录激活通过压力转移的压力.

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