相关实验视频

Updated: Sep 14, 2025

$Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain$

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain

Published on: May 10, 2017

新方法用于神经调节治疗疼痛,使用在外周周位外的最小侵入性电极来治疗疼痛

Sofia Cecchini¹, Maurits K Konings², Mienke Rijsdijk³

¹Department of Medical Technology, University Medical Center Utrecht, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.

Scientific reports

|July 18, 2025

概括

一种新的SNAP (安全神经调节对抗疼痛) 植入物避免了外周腔,为更多患者提供脊髓刺激. 这种新的设备显示了减轻疼痛的承诺,而没有增加风险,即使是那些服用抗凝药的人.

科学领域:

生物医学工程生物医学工程
神经科学是一个神经科学.
疼痛管理疼痛管理

背景情况:

慢性疼痛是一个重要的医疗保健挑战,特别是对于老年人来说.
传统的脊髓刺激 (SCS) 是有效的,但对服用抗凝剂的患者有风险,容易发生导管迁移.
由于这些限制,大量患者群体被排除在SCS福利之外.

研究的目的:

推出一种新型的多电极植入平台 (SNAP),旨在安全地进行对疼痛的神经调节.
为那些无法接受传统植入物的患者提供SCS福利,包括那些服用抗凝血剂的患者.
评估SNAP的非表皮膜安置和降低迁移风险的可行性.

主要方法:

有限元法 (FEM) 计算机模拟来评估选择性背脊柱纤维刺激.
评估SNAP能够避免不受欢迎的肌肉刺激的能力.
在体外实验证实了SNAP设备无线能量传输的可行性.

主要成果:

在FEM模拟中,通过特定电流水平 (6.30mA初级,1.26mA二级SNAP电极) 进行选择性脊柱纤维刺激.
模拟证实了避免不必要的肌肉刺激.
在体外测试中验证了SNAP系统足够的无线能量传输.

结论:

该SNAP平台介绍了一种用于疼痛管理的神经调节的新方法.
这种技术有可能克服标准SCS的局限性,包括抗凝血患者和设备迁移的风险.
该研究为SNAP的电气可行性提供了第一个概念验证,为更广泛的SCS应用铺平了道路.

关键词:

抗凝剂是一种抗凝剂.慢性疼痛是一种慢性疼痛.电场是一个电场.脊柱外腔空间是什么?引领移民引领移民带的带 (Ligamentum flavum) 是一个带.脊髓刺激是一种脊髓刺激.

更多相关视频

Breathing-controlled Electrical Stimulation BreEStim for Management of Neuropathic Pain and Spasticity

Breathing-controlled Electrical Stimulation BreEStim for Management of Neuropathic Pain and Spasticity

Published on: January 10, 2013

Author Spotlight: Insights into Remotely Supervised Neuromodulation Procedure for Phantom Limb Pain

Author Spotlight: Insights into Remotely Supervised Neuromodulation Procedure for Phantom Limb Pain

Published on: March 1, 2024

相关概念视频

Local Anesthetics: Clinical Application as Epidural Anesthesia

Local Anesthetics: Clinical Application as Epidural Anesthesia

Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...