身体构成成分与老年人骨矿物质密度之间的关联
Qi Yanmeng1, Yang Han1, Li Dandan2
1International Medical Department of Peking Union Medical College Hospital (Xidan Branch), Beijing, China.
Scientific reports
|July 18, 2025
概括
较高的身体质量指数 (BMI),骨肌肉质量 (SMM) 和无脂肪体重 (FFM) 与中年和老年人更好的骨矿物质密度 (BMD) 有关. 然而,高体脂百分比 (PBF) 可能会对骨健康产生负面影响.
科学领域:
- 老年学是一门学科.
- 整形外科 整形外科 整形外科
- 公共卫生 公共卫生
背景情况:
- 骨矿物质密度 (BMD) 对骨健康至关重要,其下降在老年人群中很常见.
- 身体组成,包括体重指数 (BMI),骨肌量 (SMM),无脂肪体重 (FFM) 和身体脂肪百分比 (PBF),可能会影响BMD.
- 了解这些关系对于开发有针对性的干预措施来维持老年人骨健康至关重要.
研究的目的:
- 调查中年和老年人身体组成和BMD之间的相关性.
- 分析这些跨不同性别和身体质量指数 (BMI) 类别的相关性.
- 确定BMI,SMM,FFM和PBF在影响BMD中的具体作用.
主要方法:
- 一项涉及1623名年龄在50岁及以上的个体的横截面研究.
- 使用双能X射线吸收计 (DXA) 测量身体组成和BMD.
- 根据BMI,被试被分为正常体重,超重和肥胖群体. 采用多重回归分析来评估相关性,并根据混因素进行调整.
主要成果:
- 在超重和肥胖的男性和女性中,增加的BMI与腰椎,左腿部部和部总体的BMD显著正相关.
- 骨肌肉质量 (SMM) 和无脂肪体质量 (FFM) 显示出与所有身体部位的BMD有显著的正相关性,无论BMI如何.
- 在肥胖男性和超重女性 (腰椎和部) 中,较高的体脂百分比 (PBF) 与骨质量有负相关性.
结论:
- 增加的BMI,SMM和FFM与中年和老年人改善的BMD有关.
- 高PBF可能会对骨健康构成风险,特别是在特定人群中.
- 保持足够的肌肉质量和健康的体重,同时管理身体脂肪,是优化老年人骨健康的建议.
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