摄入量与充血性心力衰竭风险之间的关联:来自2003-2018年NHANES数据库的横截面研究
Bo Zhu1,2, Li Wan3, Xingyu Chen1
1State Key Laboratory of Quality Research in Chinese Medicine, Faculty of Chinese Medicine, Macau University of Science and Technology, Macau, 999078, China.
BMC cardiovascular disorders
|July 18, 2025
概括
充足的摄入量可以显著降低充血性心力衰竭 (CHF) 的风险. 这项研究强调作为一种保护因素,为CHF预防策略提供了洞察力.
科学领域:
- 心血管健康 心血管健康
- 营养流行病学 营养流行病学
- 公共卫生 公共卫生
背景情况:
- 充血性心力衰竭 (CHF) 是一种主要的健康问题,其特点是心脏无法有效地血,导致液体积聚.
- 对于骨健康和肌肉功能至关重要的在预防心血管疾病中的作用尚未得到充分证实.
- 了解摄入量等饮食因素对于制定预防性健康策略至关重要.
研究的目的:
- 检查饮食摄入量与患上充血性心力衰竭 (CHF) 的风险之间的关联.
- 利用从国家健康和营养检查调查 (NHANES) 涵盖2003-2018年的数据进行强有力的分析.
- 在心血管疾病的背景下确定的潜在保护作用.
主要方法:
- 从NHANES数据集 (2003-2018) 中对3,083名参与者的横截面分析.
- 根据问卷数据将参与者分为CHF和控制组.
- 统计方法包括t测试,奇方测试,风险分层和最小绝对收缩和选择运算符 (LASSO) 回归,以确定关键预测因素并通过ROC曲线评估模型性能.
主要成果:
- 在CHF和对照组之间观察到种族,教育,禁食葡萄糖和摄入量的显著差异.
- 更高的摄入量与降低心血管衰竭的风险显著相关 (p < 0.001).
- 摄入量被确定为一个保护因素 (OR < 1) 和一个关键预测变量通过LASSO回归.
结论:
- 饮食中的摄入量显示出对充血性心力衰竭的发展有显著的保护作用.
- 这些发现表明,足够的消费可能是预防CHF的可行策略.
- 进一步的研究可以探索心血管健康的的机制和最佳水平.
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