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在类风湿性关节炎中,ZBTB16通过调节HIF-1α通路来发挥抗血管性作用

Xueqin Chen1, Yongmei Liu2, Jiangli Xia2

  • 1Department of Rheumatology and Immunology, The Fourth Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China; xueqinchen0012@163.com.

Allergologia et immunopathologia
|July 19, 2025
PubMed
概括

含有16 (ZBTB16) 的指和BTB域在类风湿性关节炎 (RA) 中降低. 过度表达ZBTB16通过阻断GRK2/HIF-1α通路来缓解小鼠的RA症状,这表明ZBTB16是潜在的RA治疗标.

关键词:
通过GRK2/HIF-1α通路.的 ZBTB1616 的情况.类风湿性关节炎 类风湿性关节炎

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