下垂体腺瘤手术后患者的疲劳轨迹及其相关因素:一项纵向研究
Xinyu Shen1,2, Mu Jin3, Yifan Wang2
1Department of Neurosurgery, The First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Suzhou, 215006, China.
概括
手术后的垂体腺瘤患者表现出不同的疲劳模式. 识别这些独特的疲劳轨迹有助于开发个性化干预措施,以改善患者的生活质量.
科学领域:
- 神经科学是一个神经科学.
- 内分泌学 在内分泌学.
- 患者的治疗结果.
背景情况:
- 疲劳是下垂体腺瘤手术后患者常见的衰弱症状.
- 这种疲劳显著影响患者的运动能力,活动水平和整体生活质量.
研究的目的:
- 为了确定不同的亚组的患者经历不同的疲劳轨迹后垂体腺瘤手术.
- 分析与这些已识别的疲劳子组相关的特征.
主要方法:
- 一项纵向研究跟踪了189名患有下垂体腺瘤的患者,这些患者经过过角膜外科手术.
- 标识后果疲劳量表在多个时间点进行,从手术前到手术后3个月.
- 增长混合模型 (GMM) 确定了疲劳轨迹组,多变量回归分析了风险因素.
主要成果:
- 确定了三个不同的疲劳轨迹:没有疲劳 (13.20%),疲劳缓解 (64.60%),持续疲劳 (22.20%).
- 疲劳轨迹的预测因素包括高强度体力活动,失业,睡眠不良,腰部排水,瘤复发和血清度低.
结论:
- 在下垂体腺瘤手术后的患者中,疲劳轨迹存在显著的异质性.
- 为医疗保健提供者推针对特定患者疲劳特征量身定制的个性化干预计划.
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