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Updated: Sep 14, 2025

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells

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一个SRRM3调节的神经替代拼接程序被颠覆,以促进胰腺神经内分泌细胞中的瘤进展

Myrto Potiri1, Charikleia Moschou2, Zoi Erpapazoglou2

  • 1Institute for Fundamental Biomedical Research, B.S.R.C. "Alexander Fleming", 16672 Athens, Greece; Department of Biochemistry & Biotechnology, University of Thessaly, 41500 Larissa, Greece.

Cell reports
|July 19, 2025
PubMed
概括

由上调的SRRM3驱动的替代拼接放松调节,在胰腺神经内分泌瘤 (PanNETs) 中改变激素分泌. 抑制SRRM3会影响PanNET的进展和神经特征.

关键词:
有关部门的官员.CP: 癌症 癌症 癌症泛网 (PanNETs) 是一个全网.在SRRM3中,SRRM3是SRRM3.替代性拼接是一种替代性的拼接.激素分泌 激素分泌 激素分泌微型外星人是微型的外星人.神经微型外表子的神经微型外表子胰腺神经内分泌瘤 胰腺神经内分泌瘤连接切换的寡核酸.

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