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Updated: Sep 14, 2025

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基伦醇通过向TWEAK/Fn14通路来缓解类风湿性关节炎

Zixin Chen1, Jinxuan Wang2, Lijuan Xiao1

  • 1College of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, P.R. China.

International journal of molecular medicine
|July 19, 2025
PubMed
概括

基伦醇 (Kir) 通过抑制TWEAK/Fn14通路,减少突细胞增殖和恢复免疫平衡来减少类风湿性关节炎 (RA) 症状. 这种化合物通过其抗炎和抗风湿作用显示出治疗RA的前途.

关键词:
纤维细胞生长因子可诱导的即时早期反应蛋白 14基伦醇 基伦醇 基伦醇类风湿性关节炎 类风湿性关节炎状纤维母细胞 状纤维母细胞类似瘤亡因子的亡因子是一种弱诱导细胞的诱导因子.

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