释放EGCG的纳米纤维支架通过γδ T细胞调节增强了伤口愈合

Tiantian An1, Zhaoyu Xu1, Yang Yang1

  • 1State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Department of Oral Implantology, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China; Frontier Innovation Center for Dental Medicine Plus, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, Sichuan, China.

Biomaterials
|July 19, 2025
PubMed
概括

这项研究表明,EGCG释放的支架显著增强了γδT细胞,通过AREG-EGFR通路促进细胞迁移和组织修复,增强了伤口愈合. 当 γδ T 细胞或这种途径被阻断时,观察到愈合障碍.

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