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Updated: Sep 14, 2025

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肝细胞癌通过欺骗胸腺,使其回忆起外围激活的CD8+ T细胞来逃避免疫监测

Qiaoting Hu1, Xuefeng Wang2, Yundan You3

  • 1Depatment of medical oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital (Fujian Branch of Fudan University Shanghai Cancer Center), Fuzhou, Fujian, PR China; Innovation center for cancer research, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian, PR China.

Neoplasia (New York, N.Y.)
|July 19, 2025
PubMed
概括

肝细胞癌 (HCC) 劫持了胸腺,以消除对瘤有反应性的CD8+ T细胞. 针对CCL19/CCL21-CCR7轴可以通过增加瘤微环境中的T细胞来恢复抗瘤免疫力.

关键词:
激活诱导的细胞死亡 (AICD)CCR7 CCR7 CCR7 CCR7 CCR7 CCR7 CCR7 CCR7 CCR7 CCR7 CCR7 CCR7CD8(+) T 细胞 细胞在HCC中,HCC是HCC,HCC是HCC.胸膜上皮细胞 胸膜上皮细胞

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