通过先进的氧化过程对阿特拉津降解溶液的急性毒性:基于质谱数据的实验性和in-silico方法
Junting Hong1, Messika Revel2, Nadia Boussetta3
1Université de Technologie de Compiègne, UPJV, CNRS, Enzyme and Cell Engineering, Centre de Recherche Royallieu, CEDEX CS 60319, Compiègne 60203, France; Université de Technologie de Compiègne, ESCOM, TIMR (Integrated Transformations of Renewable Matter), Centre de Recherche Royallieu, CEDEX CS 60319, Compiègne 60203, France; GDMPA Key Laboratory for Process Control and Quality Evaluation of Chiral Pharmaceuticals, Guangzhou Key Laboratory of Analytical Chemistry for Biomedicine, School of Chemistry, South China Normal University, Guangzhou 510006, PR China.
高压电放电 (HVED) 和高频超声波 (HFUS) 有效地降解水中的阿特拉. 这些方法比芬顿氧化更有利于环境,在水生生物中毒性较低.
科学领域:
- 环境化学环境化学
- 水处理技术水处理技术
- 生态毒理学 生态毒理学
背景情况:
- 尽管法国的地下水被禁止,但在法国地下水中仍然存在着阿特拉津残留物.
- 欧洲绿色协议需要有效的水污染物修复策略.
研究的目的:
- 通过使用高压电放电 (HVED) 和高频超声波 (HFUS) 评估自来水中的亚特拉降解.
- 评估阿特拉津降解治疗的毒理演变.
- 为了比较实验和in-silico毒性评估.
主要方法:
- 在脱离离子和自来水中评估的阿特拉津降解效率.
- 使用Daphnia magna (LC50值) 进行急性毒性测试.
- 通过液体染色学-高分辨率质谱法 (LC-HRMS) 识别转化产品.
- 使用定量结构-活性关系 (QSAR) 模型进行体中毒性评估.
主要成果:
- 在脱离离子水中,HVED和HFUS的降解效率高于自来水.
- 与HFUS (> 5 mg/L) 和HVED (1.5-2.5 mg/L) 相比,芬顿氧化导致毒性显著更高 (LC50 < 0.1 mg/L).
- 芬顿氧化的中毒性评估没有考虑残留试剂毒性.
结论:
- HVED和HFUS是降解阿特拉的高效和环保方法.
- 毒性评估对于选择可持续的水处理方法至关重要.
- 需要进一步的研究来完善用于全面环境风险评估的in-silico模型.
更多相关视频
08:49Vegetated Treatment Systems for Removing Contaminants Associated with Surface Water Toxicity in Agriculture and Urban Runoff
Published on: May 15, 2017
08:22Author Spotlight: A New and Efficient Method for Comprehensive Metabolite Cytotoxicity Assessment of Triazole Pesticides in Plants
Published on: December 22, 2023
相关概念视频
Anticholinesterase Agents: Poisoning and Treatment
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Radical Autoxidation
Oxidative Cleavage of Alkenes: Ozonolysis
Ozone is a symmetrical bent molecule stabilized by a resonance structure.
Oxidation of Alcohols
The process of oxidation in a chemical reaction is observed in any of the three forms:
