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Updated: Jul 20, 2026

Cell Type-specific Gene Expression Profiling in the Mouse Liver
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在肝细胞癌中,VEGFA 和 APOE 调节质细胞的不同功能状态:单细胞转录组分析

Xiang Lv1, Jianlin Chen2, Xieyidai Abuduhailili3

  • 1Clinical Laboratory Center, The First Huizhou Affiliated Hospital of Guangdong Medical University, Huizhou, China; Department of Laboratory Medicine, The Provincial Hospital Affiliated of Fuzhou University, Fuzhou, China.

International journal of biological macromolecules
|July 19, 2025
PubMed
概括

肝细胞癌 (HCC) 中的母细胞表现出不同的作用. 这项研究确定了四种巨细胞亚型,其中APOE与更好的结果,VEGFA与更糟糕的结果有关,这表明了新的HCC治疗策略.

关键词:
在这里,APOEOE是APOE.在HCC中,HCC是HCC.单细胞测序是一种单细胞测序.这就是TAMCs.在VEGFA中,VEGFA是VEGFA.

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相关概念视频

Cell Specific Gene Expression01:58

Cell Specific Gene Expression

Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...
Cell Specific Gene Expression01:58

Cell Specific Gene Expression

Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...