澳大利亚临床实践指南关于治疗创伤后应激障碍的甲基二氧化甲胺 (MDMA) 辅助心理治疗的制定
Alene Sze Jing Yong1, Sue E Brennan2, Suzie Bratuskins3
1Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia.
Journal of affective disorders
|July 19, 2025
概括
澳大利亚正在为MDMA辅助心理治疗 (MDMA-AP) 制定临床实践指南,以治疗创伤后应激障碍 (PTSD). 本指南旨在提供基于证据的建议,以安全有效地使用MDMA治疗PTSD.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 药理学 药理学是指药理学的学科.
- 临床实践指南 临床实践指南
背景情况:
- 在全球范围内,迷幻药的医疗用途在很大程度上仍未得到批准.
- 澳大利亚于2023年7月重新安排甲基二氧化甲胺 (MDMA) 用于授权的PTSD治疗.
- 这标志着在整合创伤后应激障碍的新疗法方面迈出了重要的一步.
研究的目的:
- 描述澳大利亚临床实践指南关于PTSD的MDMA辅助心理治疗 (MDMA-AP) 的发展.
- 为在临床环境中使用MDMA-AP制定基于证据的建议.
- 为了确保患者的安全和治疗疗效在MDMA辅助治疗PTSD.
主要方法:
- 使用推,评估,开发和评估 (GRADE) 过程的分级.
- 进行系统审查的全面概述,以评估MDMA-AP的益处和危害.
- 采用GRADE证据决策框架,考虑患者价值,资源和公平.
主要成果:
- 指南的制定涉及一个多学科的指南开发小组 (GDG).
- 关键考虑因素包括治疗的益处,危害,证据的确定性,患者的偏好和可行性.
- 综合的知识翻译方法确保了最终用户的参与.
结论:
- 该指南将在MAGICapp上发布,并通过各种道传播.
- 同行评审的出版物和专业会议将分享研究结果.
- 一个伴侣指南将支持患者,照顾者和受PTSD影响的家庭.
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