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Updated: May 5, 2026

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工程外膜囊泡 (OMVs) 携带来自S. Typhimurium的OmpA,通过AID表达和类交换机重组来针对性调节人类B细胞功能

Rahul Chaudhari1, Mallar Dasgupta1, Deveish Nigam1

  • 1Department of Biosciences and Biomedical Engineering, Indian Institute of Technology, Indore, Simrol, Khandwa Road, Indore, 453552, India.

Microbial pathogenesis
|July 19, 2025
PubMed
概括

携带OmpA蛋白 (OmpA-OMVs) 的工程外膜囊泡 (OMVs) 通过调节Toll-like受体2 (TLR2) 和促进IgA表达来激活B细胞,这表明沙门氏菌疫苗的潜力.

关键词:
激活诱导的cytidine脱氨酶 (AID) 的使用类交换机再组合 (CSR) 是一种方法.外膜蛋白 OmpAA 是一种外膜蛋白质.外膜囊泡 (OMVs) 是一种沙门氏菌进入Typhimurium类型.收费类受体2 (TLR-2) 是一种类似收费类受体.

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