食品传播的腹疫情与中国东部的Citrobacter物种有关 2022-2023年
Guilai Jiang1, Changyuan Guo1, Xin Kuai1
1Department of Microbiology, School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, 215123, China.
菌细菌导致了中国东部的食源性腹疫情. 这项研究在Citrobacter portucalensis中确定了特定的毒性和耐药性基因,突出了其作为新兴食品安全问题的作用.
科学领域:
- 微生物学 微生物学
- 食品安全 食品安全
- 基因组学就是基因组学.
背景情况:
- 杆菌属越来越多地被认为是一种机会性病原体.
- 最近在中国东部 (2022-2023) 发生的食物传播性腹疫情涉及菌种.
研究的目的:
- 调查Citrobacter portucalensis和Citrobacter freundii在最近的食物传播腹爆发中的作用.
- 描述与疫情相关的Citrobacter菌株的遗传和致病特征.
主要方法:
- 对疫情爆发病例的流行病学调查.
- 对细菌分离物的元基因组和生物信息分析.
- 在小鼠模型中进行抗菌素敏感性测试和组织学检查.
主要成果:
- 葡萄牙菌株Citrobacter portucalensis含有独特的CMY-39抗性基因和与运动性相关的特定毒性基因配置文件.
- 一种C. portucalensis菌株表现出对安培素的耐药性.
- 组织学分析显示,感染小鼠的肠子下水和炎症.
结论:
- 杆菌物种,特别是C. portucalensis,是食物传播疾病的新兴病原体.
- 对Citrobacter的监测对于食品安全至关重要,尤其是在发生疫情的地区.
- 该研究强调了被忽视的病原体,这些病原体与区域性疫情有关.
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