在文献中,处方级联是如何定义的? 一个范围审查审查
Kieran Dalton1, Perrine Evrard1, Frank Moriarty2
1Pharmaceutical Care Research Group, School of Pharmacy, University College Cork, Pharmacy Building, College Road, Cork, Ireland.
处方级联,即一种药物导致另一种药物,在研究中被不一致地定义. 本次审查强调了对标准化定义的需求,以改善这些药物问题的识别和预防.
科学领域:
- 药理学 药理学是指药理学的学科.
- 老年病的医生 老年病的医生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 处方级联是与药物相关的重要问题,特别是在患有多种健康状况和多种药物的老年人中.
- 处方级联的原始定义涉及误解药物的副作用,导致额外的处方.
- 关于副作用是否被误解,是否被识别/未识别,以及布是否有意或无意,存在争论.
研究的目的:
- 在已出版的文献中映射出处方级联的定义和描述.
- 识别处方级联如何被概念化和表示的不一致性.
主要方法:
- 针对7个电子数据库进行了范围审查,截至2024年10月.
- 包括全文英语出版物,定义或描述处方布.
- 提取了术语和视觉表示的数据,并以叙事方式进行了合成.
主要成果:
- 在包括的139个出版物中,不到一半 (48.9%) 与副作用误解的原始定义保持一致.
- 已知的/未知的副作用被提及在24.5%,适当性在37.4%,故意性在8.6%.
- 在20.9%的出版物中使用了图像或地图等视觉辅助工具.
结论:
- 在文献中如何定义和描述处方布存在实质性的异质性.
- 不一致的术语阻碍了对处方级联的识别,测量,教育和预防.
- 制定共识定义对于推进与处方级联相关的研究和临床实践至关重要.
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