通过使用ChulaPD ADL调查问卷进行全面评估,解锁帕金森症挑战的日常影响
Onanong Phokaewvarangkul1, Pattamon Panyakaew1, Jirada Sringean1
1Chulalongkorn Centre of Excellence for Parkinson's Disease and Related Disorders, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.
Scientific reports
|July 19, 2025
概括
ChulaPD ADL问卷有效地测量了帕金森病 (PD) 患者的日常功能限制. 这种可靠和有效的工具有助于评估疾病的进展及其对日常生活的影响.
科学领域:
- 神经学 神经学
- 运动障碍 运动障碍
- 临床评估工具 临床评估工具
背景情况:
- 帕金森病 (PD) 显著影响患者的日常功能.
- 准确的评估工具对于监测PD进展和治疗疗效至关重要.
研究的目的:
- 引入和验证ChulaPD ADL问卷,用于评估帕金森病中的功能限制.
- 在PD队列中评估ChulaPDADL问卷的可靠性和有效性.
主要方法:
- ChulaPD的ADL问卷,包括日常生活的15个方面的115个项目,由专家开发.
- 试点验证涉及30名PD参与者,随后对231名PD患者进行了更大的队列研究.
- 评估的相关性与已建立的措施,如霍恩和Yahr得分,MoCA和UPDRS得分.
主要成果:
- 调查问卷在试点测试中显示出强大的可靠性.
- 观察到与年龄,疾病严重程度,药物,认知功能和运动功能的分数有显著的中度至高相关性.
- 对于分级限制的13个点的门显示了81.4%的灵敏度和50.7%的特异性,用于识别姿势不稳定 (AUC=0.747).
结论:
- ChulaPD ADL问卷是一个可靠和有效的工具,用于评估PD患者日常生活活动.
- 该工具有效地捕捉了与疾病相关的变化和帕金森病患者的功能衰退.
- 它是反映疾病进展及其对日常活动的影响的相关措施.
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