在多中心病例控制研究中,ROC分析确定了Bath结脊髓炎计量指数的最佳切断和可疑间隔
Genggeng Guo1,2, Juanjuan He1, Jianwen Liu1
1Department of Rheumatology, Affiliated Shengli Hospital of Fuzhou University, Fuzhou, 350001, Fujian Province, People's Republic of China.
Scientific reports
|July 19, 2025
概括
浴结节脊柱炎计量指数 (BASMI) 评分有助于评估结节脊柱炎 (AS). 超过1.5的BASMI分数表明脊柱运动问题,而0.7到2.1之间的分数则需要进一步调查AS.
科学领域:
- 类风湿病学 类风湿病学
- 整形外科 整形外科 整形外科
- 临床测量 临床测量
背景情况:
- 浴性脊柱炎计量指数 (BASMI) 用于评估性脊柱炎 (AS) 中的脊柱移动性.
- 目前的临床实践表明,健康个体的BASMI得分通常高于零,但AS患者的下限通常被引用为零,从而造成不一致.
- 这种差异需要重新评估BASMI分数解释,以准确诊断和监测AS.
研究的目的:
- 为了建立一个更准确和临床相关的解释巴斯米得分为结性脊髓炎 (AS) 患者.
- 用接收器操作特征 (ROC) 曲线分析来确定BASMI分数的最佳切断值和可疑值区间.
- 为评估AS患者脊柱运动限制提供可靠的参考.
主要方法:
- 一项多中心病例控制研究,涉及246名AS患者和246名健康对照.
- 由训练有素的测量团队对脊柱运动的标准化评估.
- 使用SPSS26.0进行统计分析,包括ROC曲线分析,以确定BASMI分数的最佳切断和可疑值区间.
主要成果:
- 该研究确定了一般人群中最佳的BASMI截止值为1.5分.
- 对于BASMI分数的可疑值区间在0.7和2.1分之间被确定.
- 在ROC曲线下的面积为0.867,表明显著的诊断准确性 (P<0.001).
结论:
- 超过1.5的BASMI分数可能表明脊柱运动受限,尽管需要进一步验证功能和结构进展.
- 从0.7到2.1的BASMI分数需要仔细评估以确定AS的存在.
- 这些发现为解释ASMI分数在临床实践中用于AS评估提供了一个精细的框架.
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